Systems Immunology Research Group

Group leader



How does our immune system distinguish between billions of molecules? What are the main determinants of immune recognition? What factors explain that certain people are more likely to get infections or cancer, while others are protected from these diseases?

My research group aims to answer these questions. We focus on the adaptive immune system, which recognizes specific molecular motifs of pathogens, cancer and our self-cells. While this system is extremely completed, it is controlled by some less complicated laws, which we intend to characterize in detail. For example, while one would expect that the immune system is more likely to recognize molecular motifs that are highly dissimilar to our self-molecules, we showed that overly high dissimilarity hinders immune recognition. Moreover, adaptive immune recognition is largely influenced by diverse genetic factors resulting in variable susceptibility to infections, cancer and autoimmune diseases. We are focusing on a group of the most important proteins in adaptive immune recognition, the genetically extremely variable HLA molecules.

Group members


principal investigator

Balázs KONCZ

research fellow


research fellow

Franciska TÓTH

research fellow

Gergő Mihály BALOGH

PhD candidate

Benjamin Tamás PAPP

PhD candidate

Balázs SZÜCS

PhD student

Anna Tácia FÜLÖP

NTA student

Alexandra GYÉMÁNT

NTA student

Boglárka PINTÉR

TDK student

Laura BAGI

BSc student

Máté MANCZINGER principal investigator publications CV
Balázs KONCZ research fellow publications CV
Dávid KÓKAI research fellow publications CV
Franciska TÓTH research fellow publications CV
Gergő Mihály BALOGH PhD candidate publications CV
Benjamin Tamás PAPP PhD candidate publications CV
Balázs SZÜCS PhD student publications CV
Anna Tácia FÜLÖP NTA student publications CV
Alexandra GYÉMÁNT NTA student publications CV
Boglárka PINTÉR TDK student publications CV
Laura BAGI BSc student publications CV